Lupus and breast cancer treatment

Systemic Lupus Erythematosus is Not Necessarily a

The analysis reveals that among common types of cancer (in people without lupus), including breast, uterus, ovarian, pancreatic, colorectal and brain, there is no significant association. This should remind people living with lupus to be mindful of their health, but there is no cause for alarm lupus) were treated with moderate-dose to high-dose standard radiation treatment for breast cancer (four patients), Hodgkin's disease (one patient), and thymoma (one patient). None of the patients had severe acute or late radiation complications in the skin or subcutaneous tissues treated, with a follow-up of 7-12 The last main chemotherapy medication lupus patients may take is Cytoxan. It is typically used to treat leukemia, ovarian cancer, neuroblastoma, eye cancer and breast cancer, in addition to rheumatologic diseases

In another study, ulcerative colitis has shown a tentative association with breast cancer. Other connections between breast cancer and autoimmune disease are more tentative. For example, some studies have shown an increased risk of breast cancer in women with lupus, though other studies have not confirmed this Radiation treatment for cancer Lupus, as well as other systemic autoimmune illnesses such as rheumatoid arthritis or scleroderma, are chronic, lifelong diseases. Although not unusually susceptible to develop cancer, some patients with rheumatic diseases, in natural course of events, do develop other illnesses such as breast cancer

One chemotherapy drug used to treat lupus and rheumatoid arthritis is methotrexate. Many drugs used to treat one autoimmune disease also work in others because these conditions all share that.. The statistics around Black women and lupus mirror the all too familiar and troubling statistics on Black Breast Cancer: 1 in every 250 Black women will develop lupus (Lupus.org); Black women are three times more likely to get lupus than white women (CDC); The mortality rate for Black women with lupus is 3 times higher than white women with. There is a decreased risk of breast cancer in systemic lupus erythematosus (SLE) versus the general population; little is known regarding the receptor status of breast cancers in SLE, or treatment

While lumpectomy plus radiation is an excellent option for many women with breast cancer, it's not the best treatment for everyone. Lumpectomy plus radiation may NOT be right for you under the following circumstances: You have already had radiation to the same breast for an earlier breast cancer. Radiation cannot be given twice to the same area Since cancer treatment often involves chemotherapy, treatment of autoimmune illness with immunosuppressive drugs must be altered; generally the cancer chemotherapy also treats the lupus, so it is possible to withdraw most lupus treatment when a patient undergoes chemotherapy

Breast cancer in systemic lupus erythematosus (SLE

In women with breast cancer, lupus symptoms can mimic symptoms of chemotherapy or radiation, like brain fog, early menopause, and fatigue. This was the case for Shalena, who started having symptoms right after her breast cancer treatments. It was completely unexpected, Shalena remembers Breast cancer treatment is multidisciplinary. The majority of women with early-stage breast cancer are candidates for breast-conserving surgery with radiotherapy or mastectomy. The risk of local recurrence and the chance of survival does not differ with these approaches. Sjogren's syndrome, systemic lupus erythematosus, and. Credit: National Institute of Allergy and Infectious Diseases. Researchers have launched a clinical trial to test an immunotherapy drug in patients who have both cancer and an autoimmune disease, such as rheumatoid arthritis, lupus, or multiple sclerosis . Immunotherapy drugs enhance the ability of the immune system to detect and kill tumor cells

Though doctors aren't sure why lupus decreases the risk of breast cancer, the way women metabolize the hormone estrogen seems to be a factor. That said, cancer is a slim possibility, with lupus patients. Generally speaking, the same link between lupus and wrist pain - inflammation - also links lupus and breast pain There may be an increased risk of non-Hodgkin's lymphoma for those with lupus. The main link between lupus and cancer is that there appears to be an increased risk for sufferers of this condition for cancer of the lungs and non-Hodgkin's lymphoma.Non-Hodgkin's lymphoma affects the lymph nodes and other areas of the lymphatic system and is often treatable with early detection

A 42 year old Caucasian woman with a past medical history of heterozygous beta-thalassemia, photosensitivity and a family history of a mother with systemic lupus erythematosus (SLE), was diagnosed in December 2011 with metastatic breast cancer (estrogen receptor positive, progesterone receptor negative and HER2 positive). She was first. Patients with scleroderma have a statistically significant increased incidence of radiation therapy complications after breast-conserving surgery and radiation therapy. The presence of other collagen vascular diseases should not be considered a contraindication for this treatment modality The aPL are directed against different self-proteins and may cause blood clots in arteries or veins, as well as pregnancy complications. The three most common medical tests to detect aPL are: Lupus anticoagulant (LA) test. Anticardiolipin antibody (aCL) test. Anti-β 2 -glycoprotein-I antibody (aβ 2 GPI) test. 2 It's often packaged as just part of breast cancer treatment, she says. Zuckerman credits the social media groups and patient activists with pushing the FDA and plastic surgeons to re-examine the safety of implants and with assisting many individual women who felt they had nowhere else to turn The purpose of this study was to evaluate acute and late toxicities of radiotherapy for patients with discoid lupus erythematosus (DLE). A retrospective review was performed of patients with DLE who received radiotherapy at our institution between 1980 and 2005. Patients with other connective tissue disorders were excluded. Control patients were matched 2:1 with the DLE treatment courses based.

Additionally, about two in 50 men with breast cancer, have Klinefelter's. Certain testicular cancer or Leydig cell tumors, are estrogen producing as well and sadly, this may lead to an increased risk to developing lupus in some cases as well. For an in depth analysis of lupus, men, and the hormone connection by Dr. Robert LaHita, click here Occurrence of subacute cutaneous lupus erythematosus after treatment with fluorouracil and capecitabine. Weger W(1), Kränke B, Gerger A, Salmhofer W, Aberer E. (FU) prodrug recently approved for the treatment of metastatic colon and breast cancer, is currently under investigation in patients with gastric cancer. Lupus erythematosus and. A 41-year-old woman presented with pT4dN1aM0, right-sided, inflammatory breast cancer. She had a co-morbid diagnosis of systemic lupus erythematosus (SLE) at the age of 20 and was found to have.

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October of 2009 I was diagnosed with Invasive Ductile Cancer in the left breast.By the time I went in to surgery the tumor doubled in size. I opted for a double mastectomy with no reconstruction. I have had 4 rounds of Adriamycin and Cytoxan one round once every 3 weeks. Now I am on my third treatment of Taxol once a week for 12 weeks maybe we can walk this path togther I am also a Lupus pt and also with the breast cancer same as yours with the HER+2 and 2 other postive hormal factors. I have been in chemo treatment since March 2010 Hope you will be reading this post soon MAr Because of the risk of increased lupus activity, along with the risks of breast cancer and cardiovascular disease associated with HRT, treatment with HRT should be as brief as possible, says Lisa Sammaritano, MD, associate professor of clinical medicine at Weill Cornell Medical College/Hospital for Special Surgery in New York City To study the prevalence of anti‐nuclear antibodies (ANA) in breast cancer patients and its association with tumour characteristics. Ninety‐one patients with breast mass detected by image studies and assigned to conduct diagnostic biopsy and eventual surgical treatment were studied for demographical, tumour data and presence of ANA Sarcoma of the breast Patients with lupus and scleroderma Cancer during pregnancy Lymphoma of the breast Patients with limited life expectancy Special histologies (i.e., tubular, medullary, pure papillary, or colloid) 2 For inflammatory breast cancer, see Breast Cancer - Inflammatory (IBC) algorithm TABLE OF CONTENT

On the other hand, certain traditional cancer treatments may kick start autoimmune responses. The use of aromatase inhibitors for Breast Cancer may increase the risk of certain kinds of lupus. Letrozole is one example. This link has been discovered with tamoxifen and with the Breast Cancer chemotherapy drug docetaxel as well Treatment of Cancer & Lupus. Both cancer and lupus are fatal diseases, and it becomes difficult to survive if you become a victim of anyone of them. As both of the diseases don't produce prominent symptoms until they get too dangerous, so proper care is needed for the diagnosis Axillary web syndrome (AWS), also known as cording, sometimes develops as a side effect of sentinel lymph node biopsy (SLNB) or axillary lymph node dissection (ALND). Both procedures involve removing just a few (SLNB) or many (ALND) of the axillary, or underarm, lymph nodes

Redefining the Face Of Beauty : RIBBON AWARENESS

Lupus and Cancer : Johns Hopkins Lupus Cente

  1. Sometimes in medicine, a drug originally created to serve one purpose finds success in treating another condition. Such is the case in a recent study which found that a drug originally developed to boost the immune system in cancer patients is now showing promise as a potential treatment for lupus, a serious autoimmune disease where the body attacks its own organs and tissues
  2. Specific to breast cancer, fatigue is reported by a substantial majority of patients during their initial treatment (surgery, radiation, and/or chemotherapy). In addition, although estimates vary widely, approximately 33% of individuals with breast cancer report persistent fatigue up to ten years into survivorship. 6, 20, 21
  3. The cancer and autoimmune disease connection may increase disease risk, complicate treatments. October 17, 2018 | by CTCA. Cancer and autoimmunity often create challenging circumstances for doctors and patients. In patients diagnosed with either disease, these two opposing forces may collide, further complicating treatments and side-effect.

Capecitabine, an oral fluoropyrimidine recently approved by the Food and Drug Administration for the treatment of metastatic colorectal and breast cancer, is currently also under investigation in patients with gastric cancer.1, 2 It is generally well tolerated and the safety profile is considered to be excellent. Capecitabine, a carbamate derivative of 5'-deoxy-5-fluorouracil (FU), is absorbed. Lupus anticoagulants is related to both recurrent thrombosis and cancer. Thrombotic complications occur more frequently in patients with lung cancer. The aim of this study is to investigate the ass.. 4. Thompson D, Easton DF, the Breast Cancer Linkage Consor-tium. Cancer incidence in BRCA1 mutation carriers. J Natl Can -; 2002t s n r I e c : 49 . 56 - 85 31 5. The Breast Cancer Linkage Consortium Dermatomyositis, an autoimmune disease causing muscle weakness and a rash, is associated with a higher risk of several cancers, including breast, ovarian, lung and gastronintestinal tumors. Cancer is not the only reason why dimpling occurs in the breast tissue, but if the breast also feels red and warm, it may be a sign of cancer that needs urgent treatment.. Being aware of how the.

Cutaneous lupus erythematosus after treatment with paclitaxel and bevacizumab for metastatic breast cancer: A case report June 2011 Journal of Medical Case Reports 5(1):24

Flaxseed is used to: Prevent breast, prostate, and colon cancer. Control blood sugar level in patients with type-2 diabetes. Lower high cholesterol. Manage menopausal symptoms such as hot flashes and night sweats, but more research is needed to see if flaxseed actually helps with this Cutaneous lupus erythematosus after treatment with paclitaxel and bevacizumab for metastatic breast cancer: a case report Pia Vihinen1*, Outi Paija1, Atte Kivisaari2, Leena Koulu2 and Heikki Aho3. Paclitaxel is an anti-cancer agent that is used for the treatment of patients with breast cancer, ovarian cancer, gastrointestinal cancers and tumors of the head and neck. Paclitaxel treatment is often associated with neurological pain, hair loss and nail changes, but skin disorders such as photosensitivity are less common

Lupus: The Great Pretender, Breast Manifestations of SL

Mayo Clinic Q and A: Turmeric use in breast cancer treatment Nov. 09, 2020, 10:22 p.m. CDT; Expert Alert: Accelerated breast cancer treatments at Mayo Clinic provide more options for patients during pandemic Oct. 22, 2020, 04:55 p.m. CDT; Science Saturday: Mining the molecular origins of breast cancer for new cures Oct. 17, 2020, 10:00 a.m. CD As with lupus, the symptoms of lymphoma are varied and different people have differing lymphoma symptoms. Sometimes, the only symptom is a swollen lymph node: Loss of appetite, unexplained weight loss—as much as 10% or more of your body weight. Cough or chest pain, abdominal pain or fullness, rashes, and skin bumps Clinical trials have shown that DHEA is effective in treating certain forms of depression and anxiety, lupus, sexual dysfunction, and Addison's disease. High blood levels of DHEA have been associated with increased risk of breast, ovarian cancers; DHEA supplementation also resulted in flare-up of prostate cancer

Role of radiation therapy in patients with a diagnosis of

Pericardial effusions may occur with any type of cancer, but the most common include lung cancer, breast cancer, and lymphomas. With lung cancer, pericardial effusions are very common, with many people undergoing radiation therapy for lung cancer developing some degree of an effusion. Adjuvant chemotherapy (chemotherapy given after surgery. Stromal communication with cancer cells can influence treatment response. We show that stromal and breast cancer (BrCa) cells utilize paracrine and juxtacrine signaling to drive chemotherapy and radiation resistance. Upon heterotypic interaction, exosomes are transferred from stromal to BrCa cells. Inflammatory breast cancer usually starts with the reddening and swelling of the breast instead of a distinct lump. IBC tends to grow and spread quickly, with symptoms worsening within days or even hours. It's important to recognize symptoms and seek prompt treatment. Although inflammatory breast cancer is a serious diagnosis, keep in mind. Diethylstilbestrol (DES) is a synthetic form of the female hormone estrogen.It was prescribed to pregnant women between 1940 and 1971 to prevent miscarriage, premature labor, and related complications of pregnancy ().The use of DES declined after studies in the 1950s showed that it was not effective in preventing these problems

MSK's experts recommend radiation treatment after a lumpectomy to lessen the chances that the cancer will come back. This approach (lumpectomy followed by radiation therapy) is known as breast-conserving therapy. A course of radiation starts between six and 12 weeks after lumpectomy surgery. Most frequently, we target the entire breast. Most women with DCIS or breast cancer can choose to have breast-sparing surgery, usually followed by radiation therapy. Mastectomy. Most women with DCIS or breast cancer can choose to have a mastectomy. A mastectomy may be a better choice for you if: You have small breasts and a large area of DCIS or cancer The decision to offer radiotherapy in patients with connective tissue diseases continues to be challenging. Radiotherapy might trigger the onset of connective tissue diseases by increasing the expression of self-antigens, diminishing regulatory T-cell activity, and activating effectors of innate immunity (dendritic cells) through Toll-like receptor-dependent mechanisms, all of which could. Lupus is a disease of the immune system. Learn more about the symptoms, complication, causes, types, diagnosis, treatment, lifestyle changes, and outlook for lupus A subset of lupus called subacute cutaneous lupus erythematosus has been found in small-cell lung cancer patients. Additionally, people with malignant tumors or lymphomas can develop a condition resembling rheumatoid arthritis (called carcinomatous polyarthritis), which resolves when the underlying cancer is treated

How breast cancer is treated usually depends on the type of cancer, the clinical history of the patient, and how far (if any) the cancer has spread. However, most of the time breast cancer patients will undergo more than one treatment either at the same time or at different points in time. Some common treatments include When you're battling breast cancer, it can be easy to forget about your bones. Lupus & Breast Cancer: A Two-Front Battle for Black Women. The battle of breast cancer is not an easy feat. It takes strength, courage, and pure grit to undergo the journey of cancer treatment. Read More. YES, Breasties Can Get Vaccinated!.

Study Confirms Known Association Between Lupus and Cancer

A lumpectomy is often the treatment of choice for patients with early stage breast cancer, but it can be a great surgical option for many types of breast cancer. We typically recommend it for patients who have smaller, early-stage cancer, and we consider the size of the tumor compared to the overall size of the breast, Singh says And while conventional treatment for breast cancer usually involves surgery, radiation and chemotherapy, we offer a gentler, less toxic approach. Our clinic offers a combination of holistic, conventional, and alternative breast cancer treatment options. This combination has been shown to be effective for a variety of cancers over two decades The present invention concerns compounds, compositions containing these compounds, and methods of using these compounds and compositions as inhibitors of Stat3 signaling, Stat3 dimerization, Stat3-DNA binding, Stat5-DNA binding, and/or aberrant cell growth in vitro or in vivo, e.g., as anti-cancer agents for treatment of cancer, such as breast cancer

Radiation and Lupus - About Cance

  1. Dr. David Meiri, an assistant professor in the biology department at the Technion, is leading the cancer research team. Meiri, the head of Technion's Laboratory of Cancer Biology and Cannabinoid Research who did postdoctoral work at the Ontario Cancer Institute in Toronto, opened his lab in the Technion about a year ago
  2. breast cancer diagnosis and treatment. breast cancer prognosis. breast cancer screening. breast cancer screening test. breast cancer stages. breast cancer support groups. systemic lupus erythematosus. systole. systolic blood pressure. systolic pressure. taking care of diabetic foot problems. taking prescription medication
  3. We discuss the effect on cancer risk of different drug classes used in the treatment of IMIDs treatment, including biologicals such as tumor necrosis factor (TNF) inhibitors. Overall cancer incidence and mortality risk are similar to the general population in inflammatory bowel disease (IBD), and slightly increased for rheumatoid arthritis and.
  4. ation.
  5. Pleural effusion cancer life expectancy - Malignant pleural effusion is a complication involving the accumulation of fluid containing cancer cells between the membranes covering the lungs. This occurs in about 30 percent of lung cancers, but can also occur with other cancers such as breast cancer, ovarian cancer, leukemia, and lymphoma
  6. e and put forth in-depth and accurate data regarding the global Cutaneous Lupus Erythematosus (CLE) Treatment market. The report is segregated into different well-defined sections to provide.

Chemo for Lupus: Considering Chemotherapy for Treating Lupu

  1. [2]. Paclitaxel is an anti-cancer agent that is used for the treatment of patients with breast cancer, ovarian cancer, gastrointestinal cancers and tumors of the head and neck. Paclitaxel treatment is often associated with neu-rological pain, hair loss and nail changes, but skin disor-ders such as photosensitivity are less common
  2. Studies have suggested a decreased breast cancer risk in women with systemic lupus erythematosus. However, these studies enrolled younger patients identified primarily from lupus clinics. We compared the 5-year incidence of breast cancer among women with and without a diagnosis of SLE in a large population-based study of Medicare beneficiaries. We used a 20 % sample to create a cohort of.
  3. A study conducted by Johns Hopkins University discovered that when a GSTT1 gene is missing, a woman has a 1.5-fold increased risk of developing breast cancer. The health and availability of GSTs have also been shown to be key factors in the development of autoimmune conditions like lupus and rheumatoid arthritis

Recent studies have shown an increased risk of breast cancer compared to a female population of same age . Breast changes in systemic lupus are related to estrogen hyperstimulation, hyperprolactinaemia, and elevated IGF1. 4. Conclusion. Many breast changes may occur in SLE They should also stay up to date on all cancer screenings and develop good habits at decreasing their risk for infections and cancers. Being a new biologic, it will most likely be expensive. What needs to be monitored while taking anifrolumab: Your doctor will check the usual labs to follow lupus patients while you are on the treatment Cancer Drug Shows Promise Against Lupus. A drug now used to treat a type of cancer appears to be very effective at treating lupus, with just one injection easing symptoms in several patients for a. Collectively, these studies in breast cancer models suggest that quinacrine can cause apoptosis by inducing DNA damage, cell cycle arrest, and inhibition of topoisomerase activity with increased cytotoxicity in p53 knockdown breast cancer cells. Quinacrine treatment has further been shown to impact the DNA damage response in MCF-7 cells

Breast Cancer's Ties to 5 Autoimmune Disease

  1. The American Society for Radiation Oncology (ASTRO) today issued a new clinical guideline for the use of whole breast radiation therapy for breast cancer that expands the population of patients recommended to receive accelerated treatment known as hypofractionated therapy.. Breast cancer is the most common malignancy treated with radiation therapy in the United States, and whole breast.
  2. ed the likelihood of cancer recurrence for specific rheumatoid arthritis therapies
  3. Conventional Lupus Treatment. Lupus is usually treated by conventional medical doctors and rheumatologists with a combination of prescriptions and lifestyle changes. Some patients are prescribed numerous prescriptions at once and are told it takes experimenting for a while with different combinations of drugs to get symptoms under control
  4. For example, women with multiple sclerosis 22, systematic lupus erythematosus 21, and autoimmune thyroiditis 20 experienced an excess risk of breast cancer by approximately 1.5 times compared with women without these chronic conditions. Treatment of Breast Cancer in Transplant Recipients

Mayo Clinic Q and A: Turmeric use in breast cancer treatment Nov. 09, 2020, 10:22 p.m. CDT; Expert Alert: Accelerated breast cancer treatments at Mayo Clinic provide more options for patients during pandemic Oct. 22, 2020, 04:55 p.m. CDT; Science Saturday: Mining the molecular origins of breast cancer for new cures Oct. 17, 2020, 10:00 a.m. CD Primary Purpose: Treatment. Official Title: Cyberknife Radiosurgery for Early Stage Breast Cancer: A Winthrop-University Hospital Pilot Study of Cyberknife Partial Breast Radiosurgery for Tumors 3 cm or Less. Actual Study Start Date : September 2010. Actual Primary Completion Date : September 30, 2014

Elisabeth-Anne Cole, M.D., Ph.D., in Kenai treats immune dysfunction presenting as cancer-all phases, all tumors, at any location in the body, as well as AIDS, HIV, lupus, multiple sclerosis, Parkinson's disease, rheumatoid arthritis, chronic fatigue syndrome, Crohn's disease, diabetes, arteriosclerosis, and fibromyalgia. She uses nontoxic. Metastatic Breast Cancer: Human Epidermal Growth Factor Receptor 2 - negative (HER2(-)) recurrent Metastatic Breast Cancer: including systemic lupus erythematodes, Hashimotos thyroiditis, scleroderma, polyarteritis nodosa or auto-immune hepatitis. Subjects with Type I diabetes mellitus, hypothyroidism only requiring hormone replacement. Systemic lupus is a disease that can attack many parts of your body and lead to complications that sometimes require diagnosis and treatment with surgery. Surgery is not a primary treatment for. [toc]Herbal remedies are very effective for treating breast cancer, alongside medical treatment. Oncologists have provided guidelines for dietary precautions and medical strategies to counter this disease. But there are also several herbs which can be used to heal breast cancer as well. Some of these herbs are Black Cohosh, Barbed Skullcap, Blue Cohosh, Feverfew, Echinacea The breast cancer risk was not associated with any of the other SARDs, except for a risk reduction of ER-negative cases (OR=0.49, 95% CI=0.26-0.93) among women with SLE. or treatment affects.

Cancer Treatment & Cosmetic Surgery for Lupus Patients HS

  1. Some rashes occur only on the breast. Causes of rash that occur only on the breast may include: Breast abscess. Inflammatory breast cancer. Mammary duct ectasia. Mastitis (an infection in breast tissue that most commonly affects women who are breast-feeding) Nipple dermatitis. Paget's disease of the breast
  2. In 1940, Irgang introduced the term lupus erythematous profundus, for a disease in which involvement of the breast is called lupus mastitis. Lupus mastitis is a rare chronic inflammatory reaction of the subcutaneous fat that may occur in 2-3% of patients with systemic lupus erythematosis [ 3 , 4 ], usually between the ages of 20 and 50.
  3. Lupus. Types of cancer that can cause high CA-125 values include: Ovarian cancer or cancer of the fallopian tubes or endometrium. Most women with an ovarian cancer lump that can be felt in the pelvic area have CA-125 values higher than 65 U/mL. Cancer of the pancreas, stomach, esophagus, liver, breast, colon, or lung
  4. Arm morbidity is common in breast cancer treatment Arm morbidity is very common in women undergoing treatments for breast cancer. In fact, close to 90% of breast cancer treatments may result in one of a number of possible upper-extremity complications , including arm paresthesia, neuropathy, rotator cuff tendonitis and adhesive capsulities.
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With these potential health benefits, along Cbd Lupus Treatment with CBD's proven interactions with the body's endocannabinoid system to enable a sense of balance throughout various body systems, CBD may be an integral part of traditional cancer treatments in the Cbd Lupus Treatment very near future. (1 Muscle aches, also called myalgia, are a possible side effect of cancer and its treatment. You may feel an ache in a specific area of your body, or you may feel like your entire body aches. Some muscle aches are mildly uncomfortable, while others can be severe. They may last a short time or be constant for a long time Breast cancer is an invasive tumor that develops in the mammary gland. Breast cancer is detected via mammograms, breast self-examination (BSE), biopsy, and specialized testing on breast cancer tissue. Treatment of breast cancer may involve surgery, radiation, hormone therapy, chemotherapy, and targeted therapy Lupus. Lupus is a chronic condition in which the body's immune system mistakenly attacks healthy tissue. Symptoms of lupus can vary between people, depending on which tissues are attacked and how severe and prolonged the attack is. Our research is revealing how lupus develops, with the aim of improving how it is treated Approximately 25% of women will require mastectomy, but for the remaining 75%, there is a choice. The& size of the cancer in relation to the size of the breast is usually the main factor that a breast surgeon considers to determine if lumpectomy is an appropriate surgical treatment option to consider